Master courses
Advances in Radiation and Medical Physics
The term "Medical Physics" includes especially clinical work and responsibilities. It contains many different areas such as Radiation Protection in official institutions, maintenance of all parts/devices/machines that produce ionizing radiation as well as radiation treatment planning and monitoring. With regards to this broad subject, the course covers standard and advanced methods in the following main topics.
Content:
- Refreshing Medical Physics and radiation protection
- Dosimetry
- Numerical dosimetry - Biokinetics
- Numerical dosimetry - Monte Carlo Simulations
- Radiation Therapy Monitoring
- HIFU therapy
- Breath gas analysis
- Audiology Summary / new directions in medical physics e.g. AI applications
Time:
WiSe Lecture
SoSe Lab
Basics of Medical Image Science
The student will:
- Get an overview about radiation principles including types of ionizing radiation and their behaviour
- Learn about the difference between active and passive imaging methods and examples from medical imaging techniques
- Get to know system theory of medical imaging systems
- Learn to understand the differences between Fourier-based and task-based image quality descriptions
- understand how image quality can be described by different types of observers (human and model observers)
Content:
- Radiation physics for alpha-, beta-, gamma-, neutron- and X-ray radiation
- MTF, NPS and DQE
- Ideal observer, human observer models, ROC curves
Time:
SoSe
Nuclear Medicine
The students will learn about the fundamentals of physics and technology used in nuclear medicine. The course will cover the basics of radioactive processes and materials. It will then describe the various applications for diagnostic and therapeutic applications, its measurements, specific radiation protection measures and current developments including theranostics.
Content:
- Introduction - what is nuclear medicine?
- The basic elements of matter
- The nucleus
- Decay processes
- Radiation therapy with radioisotopes
- Brief overview on medical imaging with radioisotopes
- Tracers
- Specific tasks for radiation protection
- Prospects including theranostics
Time:
SoSe
Pharmacokinetic and Pharmacodynamic Modeling
The students will learn how to derive pharmacokinetic compartment models including various drugs and administration routes on different complexity scales. Additionally, fundamental knowledge of mass balances, transport phenomena and numerical simulation methods will be illustrated. The derived models will be implemented in MATLAB and the model predictions analyzed and discussed.
Content:
- Introduction into pharmacokinetic and pharmacodynamic modeling
- Pharmacokinetic and pharmacodynamic parameters
- Fundamentals for modeling biological and medical systems
- Constitutive equations and transport phenomena
- Numerical methods for solving differential equations
- Methods for optimal experimental design
Time:
SoSe
Planar Medical Imaging Techniques
The course gives an introduction to planar medical imaging technologies. Beside projectional radiography other relevant planar imaging techniques are presented. For every imaging technique we will go quickly into the image acquisition and processing and look at the key technologies that are needed to realize the individual imaging setups.
Content:
- X-ray projection radiography
- Absorption
- Dark field
- Phase contrast
- Optical imaging
- Microscopy
- Infrared
- Coherence
- Ultrasound and impedance imaging
- Examples for molecular imaging
- Magnetic nanoparticle imaging
- Scintigraphy
Time:
WiSe
Scientific Working
The skills that are essential when working as part of scientific team are collaboration with other team members, presenting results of the work and evaluation of the work of others. This course aims to strengthen these skills in the students and prepare them for active collaboration on further scientific projects.
Content:
- Prepare 20 min presentation based on the per-reviewed scientific paper from reputable journal.
- Prepare video with his/her delivery of the presentation.
- Review presentations of 2 other people.
- Respond to the reviewers regarding his/her own presentation.
- Deliver the presentation/prepare final video.
- Evaluate final presentation of two other students
Time:
SoSe
WiSe (repetition course)
Principles in clinical trials, market introduction and market surveillance of medical devices
In contrast to pharmaceuticals, no worldwide uniform legally requirements are available for the approval and CE certification of medical devices. Every manufacturer is responsible to set up the process and documentation of his medical devices to get it approved according to defines OECD Guidelines and ISO norms. The regulatory affair offers an unexpectedly exciting and diverse range of tasks for all students, especially in small and medium-sized companies. As part of the compulsory elective module, we want to deepen topics from the field of clinical studies as well as market introduction and market surveillance in this module.
Content:
The content is based on the specifications for the European CE approval and relevant DIN ISO specification. It includes following basics of the pre-market phase: Risk management and assessment, risk-benefit analysis, regulatory affairs manager, technical documentation, quality management, PDCA cycle, patient safety vs. Customer satisfaction, clinical evaluation and proof of effectiveness. After the lectures, different international admission procedures in the USA, Russia, Brazil, Japan, ASEAN, Canada, China, India, Saudi Arabia and Mexico will be examined. Therefor we will build groups of two students to perform a Term work. Content of work are selected examples to illuminate the approval procedures for different medical device classes and to address particular regulatory issues. These Term work are presented and discussed in a short lecture to all students. The homework is 50% of the examination performance. In addition, an exam is written at the end of the course, which also accounts for 50% of the total grade.
Time:
WiSe